"上海博耀生物銷售Phospho-SHIP2 (Tyr1135) Antibody #2007，CST原裝品質，價格優惠，訂購Phospho-SHIP2 (Tyr1135) Antibody #20

"上海博耀生物銷售Phospho-SHIP2 (Tyr1135) Antibody #2007，CST原裝品質，價格優惠，訂購Phospho-SHIP2 (Tyr1135) Antibody #2007，詳情請咨詢銷售人員！
產品詳細參數如下>>>>

產品名稱：Phospho-SHIP2 (Tyr1135) Antibody #2007
貨號：2007
品牌：CST(cell signaling)
抗體來源：Rabbit
克隆類型： Polyclonal
規格：

No.	Size	Price
2007S	100 ul (10 western blots)	詢價

抗體應用：

Applications	Reactivity	Sensitivity	MW (kDa)	Source
W	H	Endogenous	160	Rabbit

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度： Phospho-SHIP2 (Tyr1135) Antibody detects endogenous levels of SHIP2 when phosphorylated at Tyr1135.
來源及純化方法： Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1135 of human SHIP2. Antibodies are purified by protein A and peptide affinity chromatography.
抗體背景：

SH2-containing inositol phosphatase 1 (SHIP1) is a hematopoietic phosphatase that hydrolyzes phosphatidylinositol-3,4,5-triphosphate to phosphatidylinositol-3,4-bisphosphate (1). SHIP1 is a cytosolic phosphatase with an SH2 domain in its amino terminus and two NPXY Shc binding motifs in its carboxy terminus (1,2). Upon receptor cross-linking, SHIP is first recruited to the membrane junction through binding of its SH2 domain to the phospho-tyrosine in the ITIM motif (2), followed by tyrosine phosphorylation on the NPXY motif (2). The membrane relocalization and phosphorylation on the NPXY motif is essential for the regulatory function of SHIP1 (3-5). Its effect on calcium flux, cell survival, growth, cell cycle arrest and apoptosis is mediated through the PI3K and Akt pathways (3-5). Tyr1021 is located in one of the NPXY motifs in SHIP1, and its phosphorylation is important for SHIP1 function (6).

關鍵詞：CST，抗體，一抗{byao_back}{byao_back2}

相關產品：
ab10387/Anti-GRO beta antibody
ab103840/Anti-CaMKII antibody
Anti-CD10/CALLA/NeprilysinCD10抗體
ab103091/Anti-CA5B antibody
Anti-beta-Amyloid(25-35)β淀粉樣肽（25-35）抗體
ab102625/Anti-CHCHD1 antibody
ab101929/Anti-Connexin 40 / GJA5 antibody
Anti-Smad7/Smad6Smad 7抗體
Anti-DDX58DDX58抗體
Anti-OPCML阿片樣物質結合蛋白/細胞粘附分子樣蛋白抗體
ab101358/Anti-GALNT12 antibody
ab10059/Anti-Cardiac FABP antibody
ab100889/Anti-ADO antibody
Anti-HLA G(N-Terminus)人類白細胞抗原G抗體（N端）
Anti-TBX2/T-box2血栓素B2抗體(一種新發現的抑癌基因)
ab103086/Anti-eRF3B/GSPT2 antibody"
本頁產品地址：http://lgsztm.com/sell/show-3242092.html